Iron is an important trace element in the human body. The lack of iron often causes iron deficiency anemia. Pregnant women affect the absorption of iron elements due to various factors such as pregnancy reactions and gastrointestinal motility during pregnancy.The demand for internal iron is easy to cause iron deficiency anemia for pregnant women.Studies have shown that iron deficiency anemia has a high prevalence among pregnant women.Iron deficiency anemia can cause serious harm to pregnant women and fetuses.
Postpartum hemorrhage is a common clinical childbirth complications, and one of the main causes of maternal death.Studies have shown that anemia is one of the risk factors of postpartum bleeding. With the increase of iron deficiency anemia, postpartum bleeding incidence will gradually increase.
Postpartum hemorrhage refers to within 24 hours after the fetus is delivered, the amount of bleeding from vaginal delivery is ≥500ml, and the amount of bleeding from the cesarean section is ≥1000ml;
Severe postpartum bleeding refers to the amount of hematopoietic amount within 24 hours after delivery of the fetus ≥1000ml;
Practicing postpartum hemorrhage refers to conservative measures such as blood contraction, persistent uterine massage or pressing, and cannot stop bleeding. It requires surgical surgery, intervention therapy, and even remove the severe postpartum bleeding of the uterus.
During pregnancy, the demand for iron is more than double than before pregnancy. If the pregnant mother is accompanied by iron deficiency before pregnancy, the demand for iron after pregnancy should be increased more.If the iron intake is insufficient, pregnant mothers can easily suffer from iron deficiency anemia.
Pregnant women’s anemia during pregnancy can cause decreased resistance, and patients usually show symptoms such as palpitations, insomnia, and dizziness.In addition, the tolerance of anemia pregnant women to childbirth and surgery decreases, and the risk of complications of production sections increases, which not only affects the recovery of the maternal, but also may affect fetal health.
Iron elements are the necessary raw materials necessary for red blood cells and hemoglobin (HB) to survive. The amount of pregnancy during pregnancy has significantly improved. Pregnant women need exogenous intake to ensure the body’s iron cycle balance.If iron intake does not pay attention to iron during pregnancy, it is difficult for pregnant women to actively absorb iron to meet their demand, and long -term can cause iron to gradually develop to iron deficiency anemia.
In order to meet the needs of fetal growth and development during pregnancy, the circulating blood volume of pregnant women will increase, and the increase in blood capacity will lead to blood dilution, causing the body’s HB concentration to decrease. Usually the HB concentration in the early pregnancy starts to fall.normal level.
Studies have shown that compared with measures such as iron -containing diet and improving health awareness, supplementary iron supplements according to specifications are a more effective way to improve the level of HB.
(1) Commonly used oral iron drugs mainly have the following:
① The first generation of oral iron agent: sulfate iron iron
It is an inorganic rail, with high iron content and cheap price. It is a commonly used oral iron agent.However, its properties are unstable, absorb in the form of ions, are susceptible to interference by other ingredients, poor biological utilization, significant gastrointestinal irritation, and large rust flavor.
② Second -generation oral iron agent: lactic acid metal iron
The lactate ferrite is the representative of the second -generation oral iron in organic acid. Similar medicines also include citrate ferrite, amber -ferrite, and fogamic acid.The common feature is absorption in the form of ion, which is easily disturbed by other ingredients. The free FE2+leads to the production of endogenous free radicals and damage the cell membrane.
③ The third -generation new organic iron: right lattahydride iron
The results of the study show that the treatment of right -deronned iron scattered tablets is effective and highly safe.Rightrarohin anhydride iron is the third -generation oral iron. The main component is based on iron complication and right Forraphylasses. It is a soluble iron element. After the drug enters the human body, the rightrahin anhydride iron can effectively supplement the iron element required by the patient’s bloodIt is conducive to alleviating clinical symptoms.
Related studies have shown that the soluble capacity of right -ramoseine iron scattered tablets is more likely to be absorbed by the human body. Different doses are selected according to the degree of anemia degree, which can ensure the safety of medication, but also fully supplement the iron content, and the effect is obvious.In summary, the clinical efficacy of right -tabichin -iron decentralized tablets to treat pregnancy and iron deficiency anemia is precise, which can effectively improve the symptoms of anemia, reduce the ending of adverse pregnancy, and have high safety. It is worthy of clinical promotion and application.
Affected by iron deficiency, matrix metal proteases may be overwhelmed, causing uterine levels of smooth muscle contraction and fatigue, induced postpartum bleeding, and the occurrence of iron deficiency anemia can also cause uterine ischemia and hypoxia, affect fetal nutrition and metabolism, and cause fetal dysplasia.
Iron supplementation during pregnancy should adopt individual iron supplement strategies to master the appropriate time and reasonable dose to reduce the incidence of hypertension and premature breakthroughs during pregnancy, and reduce organ dysfunction and low birth weight caused by anemia.At the same time, the oxidation stress reaction caused by high -dose iron and excessive iron should also be avoided.
In summary, iron supplementation of iron deficiency anemia during pregnancy is conducive to reducing the incidence of postpartum bleeding and bleeding, improving hemoglobin levels and immune function, and reducing the incidence of adverse pregnancy ending.
Reference materials:
[1] Xu Kesu, Zhang Yan, Wang Yun, Zheng Xiaoyi. Iron supplementing the effects of post-gardening of iron deficiency anemia and the impact on the level of hemoglobin [J]. Chinese women and children’s health research, 2022,33 (06): 62-66Then, then
[2] Zhang Yu. The clinical efficacy and safety of the dextrase anhydride iron decentralized tablets to treat the clinical effect of pregnancy and iron deficiency anemia [J]. Clinical reasonable medication magazine, 2020,13 (21): 127-128.
