"Liu Changwei" talks about the things of probiotics and babies are allergic to the baby

China Clinical Nutrition Network (LCYYCC)

about the author

Liu Changwei

"China Clinical Nutrition Network" expert consultant and signing author

Master of Nutrition, Nutrition Physician of Nanjing Children’s Hospital affiliated to Nanjing Medical University

Entering child nutrition and diet guidance, and nutritional support under different diseases.

Popular science author, edited "Baby, What to Eat Breakfast", "Liu Changwei to let the baby get sick", etc.

In 2015, he was included in the Nanjing Children’s Hospital "Qingmiao Talent".

Public WeChat/Sina Weibo: Children’s Nutritionist Liu Changwei, share the knowledge of parenting nutrition and nutrition science, Weibo fans 200,000+.

Talk about those things that are allergic to probiotics and babies

Speaking of probiotics can be used for the baby’s diarrhea, to support the intestinal flora, everyone is no stranger, but to say that probiotics can be used to prevent the baby’s allergic diseases. Many people estimate that it is incredible and is actually based on it.

1. What is probiotics, what do you look like?

Fuller proposed in 1989 that probiotics can be obtained from the outside world that can have a beneficial effect on the host by improving the intestinal micro -ecological balance.As a microorganism that is beneficial to human health, probiotics can regulate and maintain the intestinal micro -ecological balance by making up for the shortcomings of the normal intestinal flora.The United Nations Food and Agriculture Organization (FAO) and the World Health Organization (WHO) believe that probiotics "as part of the diet, and the microbes that are beneficial to the health of the host after intake".

2. How does the intestinal flora and allergic diseases have a relationship?

The incidence of allergic diseases such as asthma, eczema, allergic dermatitis, allergic rhinitis, and food allergies increases year by year, affecting the growth and development of infants and young children.The causes of allergic diseases are more complicated, mainly related to environmental, genetic, immune and other factors.The more recognized "hygiene hypothesis" believes that due to the improvement of sanitary conditions, miniaturization of family, and the use of a large amount of antibiotics, it is rarely exposed to the microbial environment after birth.The incidence of allergic diseases in children has increased.Lack of microbial stimulation in the early days of life, the immune system tends to respond to allergies. After giving microorganisms, the immune system tends to respond to restore TH1/TH2 to balance, reduce and avoid the occurrence of allergic diseases.

Probiotics are defined as a living bacteria that can produce beneficial effects on the host.In their multi -efficiency effects, inhibit the pathogen of the pathogen on the surface of the mucous membrane and the regulating immune response is widely considered to be the main biology activity of probiotics [1].

3. Probiotics to prevent eczema, really fake?

A foreign probiotic and/or probiotic analysis of META in preventing eczema. The results show that pregnant women or lactating women or their offspring oral probiotics and/or preyrodeds.However, the incidence of eczema of eczema taking probiotics has not changed significantly [2].In addition, the incidence of eczema was reduced by 42%after combining withborcus and bisidobacterium.Many studies have shown that probiotics have potentially reducing the risk of infant eczema, but the best probiotic intervention solutions have not yet been determined.

In another study, probiotics were given to mothers, not babies.Study whether women supplement probiotics during pregnancy and breastfeeding can reduce the risk of eczema of high -risk infants.This is a 241 parallel, double -blindness, and placebo control test for maternal and infants. Mothers with allergic diseases and characteristic sensitivity are randomly assigned and accepted.; (2) Piccinobacterium ST1 and Changzangqi BL999, or (3) placebo, the test began 2 months before childbirth and the first two months of breastfeeding.Babies followed up to 2 years old and performed skin thorns at the baby 6, 12, and 24 months.The results showed that the mothers who received LPR+BL999, the risk of eczema in the first 24 months of life was significantly reduced.The results of the study suggest that the specific probiotics of pregnant women and mothers during the prenatal and postpartum mothers can safely and effectively reduce the risk of eczema of the baby’s infant of the skin.

A domestic META analysis is based on the existing evidence to obtain the following conclusions: Mothers with allergic diseases family history and infant children take probiotics and (or) postpartum infants to continue to take probiotics, which can reduce infants and young children degeneration.The incidence of sexual eczema has a preventive effect, but it has no prevention of food allergies and asthma, and needs to be further studied [4].

4. Early use of probiotics can reduce the symptoms of incentive allergies

Early life taking probiotics can effectively reduce the level of IgE and reduce the symptoms of characteristic allergies, especially early prevention for children with high -risk allergies.Studies have confirmed that effective strains are GG plants and emulsions of mice and lactobacillus, and in vitro and clinical studies have shown that lactobacillus and bisidobacterium may have synergistic effects.Therefore, the use of mixed strains may be a strategy to effectively reduce eczema in infants and young children.Studies have shown that the mother’s supplementation of mouse Li candy during pregnancy and breastfeeding can increase the concentration of immune regulating cytokines-metastasis growth factor (TGF) -β2 in breast milk, which is related to reducing infant eczema.Maternal maternal probiotics intervention seems to be safe, cheap, and relatively easy to implement.In the last two months of pregnancy and two months before breastfeeding, pregnant women supplemented the risk of eczema of eczema of high -risk babies.However, more evidence may be required to further support this view.Of course, everyone’s supplement is obviously not wise and rational use.

5. Probiotics knowledge Tips

(1) Q: Can all probiotics be used to prevent and treat eczema?

Answer: No.Judging from the current research data, there are not too many strains used to prevent eczema in infants and young children. Only specific strains are sufficient, such as Rat Lijugang LGG and Lactobacteriobacterium BB-12.At present, in addition to the market in the market, there are mice logg LGG and Milky Bacteria BB-12 mixed strain, as well as a single strain of mouse Liquor bacteria.

(2) Q: What are the forms of probiotics?

Answer: From a morphological point of view, there are powder, capsules and drops.At present, powder and capsules on the market are more common, and they are generally used for children.There are not many drops of ticks, such as Italy’s latest launch of Rat Liusacchide LGG drops.

(3) Question: Does the type of probiotics and the amount of bacteria affect the efficacy of it?

Answer: Yes.Probiotics should have an impact on the effect of bacteria and bacteria. Only specific bacteria can be used to treat eczema.The amount of bacteria also affects the curative effect. If the amount of bacteria is too small, the amount of bacteria that reaches the intestine after taking it is limited, and the effect of health or treatment may not be available.From the perspective of the amount of bacteria that are commercially available, some of them have 10 million yuan, and some exceed 150 million, some of which are 3 billion, 5 billion, or even 6 billion.Rone and bacteria.Specifically, you need to consult a doctor or professional nutritionist or related professionals.


1. Paul V. Licciati, Intan H. Ismail, Anne Balloch, et al. ET Al. ISK of Developing Allergic Disease [J]. FRONT Immunol, 2013

2. Dan dang, wenli zhou, et al. Meta-Nanalysis of Probiotics and/OR Prebiotics for the Prevention of eczema.

4. Tang Lujing, Chen Jie, Shen Yi, probiotic analysis of probiotics to prevent children’s allergic diseases. Chinese Pediatric Magazine, 2012

Editorial Department of "China Clinical Nutrition Network"

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